Most clinical studies that apply and test brain-machine interfaces are focusing on restoration of movement or communication. Besides these important fields, also other applications are now increasingly tested, e.g. in the context of neuropsychiatric disorders, e.g. in depression, autism or Alzheimer’s disease.
Restoration of Movement
ALS (Amyotrophic Lateral Sclerosis)
Tetraplegia / Quadriplegia
Stroke
Restoration of Communication
ALS (Amyotrophic Lateral Sclerosis)
Study | Status |
First Study With a Brain Implant to Help Locked-in Patients Communicate at Home (UNP) |
Recruiting |
Brain Computer Interface Complete locked-in State Communication. University Hospital Tuebingen |
Recruiting |
An In-home Study of Brain Computer Interfaces University of Michigan |
Completed (May 2011) |
Communication by Brain – Computer Interface in Amyotrophic Lateral Sclerosis:Feasibility Study |
Unknown |
Tetraplegia / Quadriplegia
Study | Status |
Brain Implant for Neural Control of a Computer |
Recruiting |
Robust Intelligent Keyboard for Quadraplegic Patients |
Recruiting |
Brain Computer Interface for Communication in ICU: a Feasibility Study |
Completed (May 2012) |
Other
Alzheimer´s Disease
Study | Status |
Neurofeedback in Alzheimer’s Disease Oregon Health and Science University |
Not yet recruiting |
Brain-Computer Interface System for Training Memory and Attention in Elderly Duke-NUS Graduate Medical School, Duke University |
Completed (June 2017) |
Effectiveness of a Brain-Computer Interface Based System for Cognitive Enhancement in the Normal Elderly Duke-NUS Graduate Medical School |
Completed (April 2014) |
Autism
Study | Status |
Brain-Computer Interface-based Programme for the Treatment of ASD/ADHD (ASDBCI) Duke-NUS Graduate Medical School |
Recruiting |
BCI (Brain Computer Interface) Intervention in Autism IBILI – Institute for Biomedical Imaging in Life Sciences |
Completed (September 2018) |
Rt-fMRI NF Intervention Study in ASD IBILI – Institute for Biomedical Imaging in Life Sciences |
Completed (September 2018) |
Depressive Disorders
Study | Status |
Affect Regulation Based on Brain-computer Interface Towards Treatment for Depression Institute of Mental Health, Singapore |
Completed (September 2018) |
Symptom Based Treatment Affects Brain Plasticity – Cognitive Training in Patients With Affective Symptoms (APIC-II) RWTH Aachen University |
Not yet recruiting |
A Feasibility Study to Evaluate Safety and Initial Effectiveness of ExAblate Transcranial MR Guided Focused Ultrasound for Bilateral Anterior Capsulotomy in the Treatment of Medication-Refractory MDD Yonsei University |
Completed (July 2018) |
Fibromyalgie
Study | Status |
Neurofeedback for Fibromyalgia Institute of Pain Mecine, Tel Aviv Sourasky Medical Center |
Unknown |
Epilepsy
Study | Status |
Brain Computer Interfaces for Functional Recovery From Brain Injury University of Washington |
Recruiting |